Kanika made her debut in the 2002 Tamil film Five Star, she went on to work in other South Indian film industries, including Telugu, Malayalam and Kannada, as well. She is perhaps best known for her performances as Eashwari in her debut film Five Star, Gayathri in Varalaru - History of Godfather and Thenmozhi in Autograph. She made waves in the Malayalam film industry with back to back successful films Bhagyadevatha and Pazhassi Raja.